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Effects of adipocyte ablation on RPE/choroid complex in mice

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE261183
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Adipocytes are essential for mainteining homeostatic status of multiple organs. Here we report that adipocytes ablation leads to pro-inflammatory state of retinal pigent epithelium/choroid complex in the eye. iDTR (iDTR (C57BL/6-Gt(ROSA)26Sortm1(HBEGF)Awai/J) mice expressing adiponectin-Cre were treated with intraperitoneal injection of diphtheria toxin every day for 7 weeks. RPE/choroid complex samples were collected from eyes.
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2025-03-31
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