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Deregulated long non-coding transcripts in M1 and M2 macrophages

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE195440
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Non-coding transcripts make up around 98 % of RNAs in the transcriptome of cells, while only around 2 % are coding for proteins. Long non-coding RNAs (> 200bp) are known to have high regulatory functions in various cellular processes. Here, we aimed to characterize the distinct macrophage phenotypes regarding their expression of long non-coding RNAs, which might be involved in the activation process. RNA-sequencing of PBMC derived unstimulated (M0) or in vitro polarized (M1 or M2) macrophages
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2023-08-28
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