Gene expression profiling of Male and Female adult mouse liver using RNA-seq

Liver sex-specific long noncoding RNAs (lncRNAs) were identified based on three pools of male and three pools of female ribosomal RNA-depleted total liver RNAs, as well as three pools of male and three pools of female ribosomal RNA-depleted nuclear liver RNAs from CD-1 mice. This dataset is part of a larger study, entitled "Sex-biased lncRNAs inversely correlate with sex-opposite gene co-expression networks in Diversity Outbred mouse liver", Endocrinology (2019) 160:989-1007, PMID:30840070. Identification of liver sex-specific lncRNAs and RefSeq genes using rRNA-depleted total and nuclear RNA isolated from male and female mouse liver.本研究基于CD-1品系小鼠的3份雄性肝脏总RNA混合池、3份雌性肝脏总RNA混合池（均经核糖体RNA去除处理），以及3份雄性肝脏细胞核RNA混合池、3份雌性肝脏细胞核RNA混合池（均经核糖体RNA去除处理），鉴定得到肝脏性别特异性长链非编码RNA（long noncoding RNAs，lncRNAs）。本数据集隶属于一项更大规模的研究，该研究题为《多样性远交小鼠肝脏中性别偏向性lncRNAs与性别相反基因共表达网络呈负相关》，发表于《内分泌学》（Endocrinology，2019年，160卷：989-1007），PubMed编号（PMID:30840070）。本数据集的研究内容为利用从雌雄小鼠肝脏中分离的经核糖体RNA去除处理的总RNA与细胞核RNA，鉴定肝脏性别特异性lncRNAs与参考序列基因（RefSeq genes）。