Crystal structure of BACE1 in complex with aminooxazoline xanthene 9l
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Crystal structure of BACE1 in complex with aminooxazoline xanthene 9l Descriptor: (4S)-2'-(5-chloro-2-fluorophenyl)-7'-methoxyspiro[1,3-oxazole-4,9'-xanthen]-2-amine, Beta-secretase 1, DIMETHYL SULFOXIDE, ... Authors: Whittington, D.A, Long, A.M. Deposit date: 2012-06-26 Release date: 2012-09-12 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structure- and Property-Based Design of Aminooxazoline Xanthenes as Selective, Orally Efficacious, and CNS Penetrable BACE Inhibitors for the Treatment of Alzheimer's Disease. J.Med.Chem., 55, 2012
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2012-06-26
