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Evidences for the Leukemia of the identified biological pathways.

NIAID Data Ecosystem2026-05-02 收录

数据链接：

https://figshare.com/articles/dataset/Evidences_for_the_Leukemia_of_the_identified_biological_pathways_/28963543 数据链接链接失效反馈

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Evidences for the Leukemia of the identified biological pathways.

应用场景：

创建时间：

2025-05-08

造血干细胞表观遗传学

白血病发病机制

Aging is associated with functional decline of hematopoietic stem cells (HSC) as well as an increased risk of myeloid malignancies. We performed an integrative characterization of epigenomic and trans

NIAID Data Ecosystem50

Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis [TargetedCRISPRscreen]

白血病发病机制

CRISPRi筛选

Investigating Bcor target genes in BcorΔE9-10KrasG12D leukaemia with a custom CRISPR dropout screen BcorΔE9-10KrasG12D cell line was transduced with a custom CRISPR library and a dropout screen was pe

NIAID Data Ecosystem30

Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation

干细胞研究

白血病发病机制

Additional Sex Combs Like 1 (ASXL1) is frequently mutated in myeloid malignancies and clonal hematopoiesis of indeterminate potential (CHIP). Although loss of ASXL1 promotes hematopoietic transformati

NIAID Data Ecosystem10

Separate combinations of regularisation parameters, and used for analysis of the SP2 dataset.

多组学特征选择

微生物通路分析

For each , combination, the mean (±SD) number of selected pathways and SNPs across all 1000 subsamples is reported.

NIAID Data Ecosystem30

Significantly Affected Pathways After Virtual Knockout of Key Genes.

基因功能模块

微生物通路分析

Significantly Affected Pathways After Virtual Knockout of Key Genes.

Figshare2025-11-07 更新20