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Discovery of anti-virulence drugs against Pseudomonas aeruginosa infections
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2023-09-08
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Exposure of cystic fibrosis bronchial epithelial cells (CFBE 41 o-) to Pseudomonas aeruginosa (PA01) biofilms. Homo sapiens
In the clinical setting, mutations in the CFTR gene enhance the inflammatory response to P. aeruginosa (PA01) infection, but measurements of the inflammatory response to pathogen stimulation by isolat
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Overlaps between PA14-induced genes identified in this study and previously reported PA14-driven genes.
Overlaps between PA14-induced genes identified in this study and previously reported PA14-driven genes.
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Pathological, flow cytometry, cytokine, and RT-qPCR results at different time points before and after Pseudomonas aeruginosa infection.
Pathological, flow cytometry, cytokine, and RT-qPCR results at different time points before and after Pseudomonas aeruginosa infection.
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Characteristics of the study group.
Abbreviations: FEV1% Forced experatory volume in one second expressed as percentage of predicted, P.aeruginosa; Pseudomonas aeruginosa.
NIAID Data Ecosystem90
Plant-expressed pyocins for control of Pseudomonas aeruginosa
The emergence, persistence and spread of antibiotic-resistant human pathogenic bacteria heralds a growing global health crisis. Drug-resistant strains of gram-negative bacteria, such as Pseudomonas ae
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