Unconventionally-acting PROTACs promote mitochondria health by enhancing ubiquitination-dependent mitophagy
收藏Mendeley Data2026-04-09 收录
官方服务:
资源简介:
Original data of this manuscript
应用场景:
相关数据集
Supplementary Table 2 from Phosphorylation of Parkin at serine 65 is essential for its activation in vivo
Mutations in PINK1 and Parkin result in autosomal recessive Parkinson's disease (PD). Cell culture and in vitro studies have elaborated the PINK1-dependent regulation of Parkin and defined how
DataCite Commons2020-08-28 更新130
Receptor Mediated Mitophagy
This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which al
reactome.org60
Additional file 10 of Cullin-RING ligase BioE3 reveals molecular-glue-induced neosubstrates and rewiring of the endogenous Cereblon ubiquitome
Supplementary Material 10. Supplementary Table 2. LC-MS/MS processed data of CRBN BioE3 with proteasomal inhibitor bortezomib, with or without NEDDylation inhibitor MLN4924. Gene Ontology analysis of
NIAID Data Ecosystem50
Rational discovery of Cyclin K molecular glue degraders via scalable chemical profiling
Targeted protein degradation is a new paradigm in drug development that promises to overcome limitations of traditional pharmacology. It is based on small molecules that induce proximity of a target p
NIAID Data Ecosystem90
Near-Infrared-Activatable PROTAC Nanocages for Controllable Target Protein Degradation and On-Demand Antitumor Therapy
As a novel protein knockdown tool, proteolysis targeting chimeras (PROTACs) can induce potent degradation of target proteins by hijacking E3 ubiquitin ligases. However, the uncontrollable protein disr
Figshare2023-06-06 更新60



