Growth characteristics, adiposity and lipid accumulation.

Three-month-old mice were placed on various diets and killed after 8 weeks of the dietary treatment as described in Methods. Body weight and food consumption (FC; recorded weekly) data are related to the initial 6 weeks of the treatment; due to irregularities of the body weight and FC data caused by glucose tolerance test performed during week 7, data from the last 2 weeks of the treatment could not be included (see Fig. 1). Fat depot weights and levels of plasma leptin were recorded after the killing. Expression of SCD-1 gene in the liver was evaluated using quantitative RT-PCR analysis and standardized using elongation factor 1α (Gene ID: 13627). Data are means±SE (n = 7-8).aSignificantly different from cHF.bsignificantly different from cHF+F.csignificantly different from cHF+ROSI.dsignificantly different from cHF+F+ROSI.esignificantly different from cHF+PIO (ANOVA).fSignificantly different from Chow (t-test).