Figure 3

BMK-DKO cells expressing CBcl-2, transfected with VBH3 proteins. Data displayed in Figure 3 was generated from combining results of 4 screens: 1) BclXL_Bcl2_screen {Rep1_20180822, Rep2_20180823, Rep3_20180830, Rep4_20180831} 2) mim2_Bcl2_screen {Rep1_20190326, Rep2_20190327, Rep3_20190328, Rep4_20190329} 3) XL2W_screen {Rep1_20191108, Rep2_20191109, Rep3_20191110, Rep4_20191111} 4) PumaV_screen {Rep1_20200909, Rep2_20200910, Rep3_20200916, Rep4_20200917} -For each screen, see "Master Platemap" for screen design as well as data generated in qF3 analysis step 8_CombineBinnedReps: Here are, "combined_WellID_binnedReps_.csv" data files, that were fit to determine live cell Kds. Exported result from fitting these data is also included in, "CombinedBinnedReps_Results.xlsx". -Figure 3a-c shows the average of controls (VBH3 proteins and corresponding collisional control: VBH3-4E) included in each of these screens. (See "Summarized_CBcl2_ Results.xlsx").