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Genome wide screen of estrogen receptor Î± regulated microRNAs reveals a negative autoregulatory feedback loop

ChEBI2010-06-25 更新2026-07-21 收录

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MicroRNA调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-14685 数据链接链接失效反馈

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Genome wide screen of estrogen receptor Î± regulated microRNAs reveals a negative autoregulatory feedback loop

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创建时间：

2010-06-25

组织特异性表观遗传学

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Estrogen has vascular protective effects in premenopausal women and in women under 60 receiving hormone replacement therapy. However, estrogen also increases risks of breast and uterine cancers and of

NIAID Data Ecosystem100

Temporal transcriptional response from primary human chronic lymphocytic leukemia (CLL)-cells after B-cell receptor stimulation.

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慢性淋巴细胞白血病转录组

The B-cell receptor (BCR) signaling is crucial for the pathophysiology of most leukemias and lymphomas originated from mature B lymphocytes and has emerged as a new therapeutic target, especially for

NIAID Data Ecosystem40

Table2_Isoprenaline and salbutamol inhibit pyroptosis and promote mitochondrial biogenesis in arthritic chondrocytes by downregulating β-arrestin and GRK2.DOCX

关节炎治疗机制

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Rheumatoid arthritis and osteoarthritis overlap many molecular mechanisms of cartilage destruction. Wear and tear in cartilage is chondrocyte-mediated, where chondrocytes act both as effector and targ

NIAID Data Ecosystem30

Analysis of estrogen-induced mRNA in endometrial cancer cells with forced expression of ER. Analysis of estrogen-induced mRNA in endometrial cancer cells with forced expression of ER

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子宫内膜癌转录组分析

We used the endometrial adenocarcinoma cell line in which the ERα cDNA gene was transfected and forcedly expressed ER. Then the factors induced by estrogen (Estradiol: E2) were measured by microarray.

NIAID Data Ecosystem50

GO:0004879 (nuclear receptor activity)

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生物分子网络

This network was assembled automatically by INDRA (http://indra.bio) by processing all available biomedical literature with multiple machine reading systems, and integrating curated pathway databases.

NIAID Data Ecosystem40

Genome wide screen of estrogen receptor Î± regulated microRNAs reveals a negative autoregulatory feedback loop

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