Crystal structure of the human HIPK3 kinase domain bound to abemaciclib
收藏Protein Data Bank Japan2024-11-13 更新2026-04-19 收录
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Crystal structure of the human HIPK3 kinase domain bound to abemaciclib Descriptor: Homeodomain-interacting protein kinase 3, N-{5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl}-5-fluoro-4-[4-fluoro-2-methyl-1-(propan-2-yl)-1H-benzimidazol-6-yl]py rimidin-2-amine Authors: Kaltheuner, I.H, Anand, K, Geyer, M. Deposit date: 2021-04-13 Release date: 2021-11-24 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.81 Å) Cite: Abemaciclib is a potent inhibitor of DYRK1A and HIP kinases involved in transcriptional regulation. Nat Commun, 12, 2021
创建时间：
2021-04-13
