成纤维生长因子受体FGFR数据

数据集包含aFGF改善糖尿病诱导的血管内皮损伤新机制相关数据；bFGF缓解糖尿病条件下血管内皮细胞功能紊乱新机制相关数据；FGF10通过作用于FGFR2b缓解肝脏氧化应激的机制研究相关数据；FGFR1信号调控高血压的新机制相关数据。

This dataset includes data associated with four sets of mechanistic research: 1. Novel mechanisms underlying acidic fibroblast growth factor (aFGF)-mediated amelioration of diabetes-induced vascular endothelial injury; 2. Novel mechanisms underlying basic fibroblast growth factor (bFGF)-mediated alleviation of vascular endothelial cell dysfunction under diabetic conditions; 3. Data related to mechanistic studies demonstrating that fibroblast growth factor 10 (FGF10) mitigates hepatic oxidative stress by acting on fibroblast growth factor receptor 2b (FGFR2b); 4. Novel mechanisms whereby FGFR1 signaling regulates hypertension.

搜集汇总

背景与挑战

背景概述

该数据集聚焦于成纤维生长因子受体（FGFR）在疾病机制中的研究，主要包括aFGF、bFGF、FGF10和FGFR1在糖尿病、肝脏氧化应激和高血压等相关病理过程中的新机制数据。数据集由南京大学发布，包含5个文件，总数据量81.84MB，源自国家重点研发计划项目，旨在支持糖尿病并发症的药物靶点研究。