Crystal structure of human Brachyury in complex with a single T box binding element DNA
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Crystal structure of human Brachyury in complex with a single T box binding element DNA Descriptor: DNA (5'-D(*AP*GP*GP*CP*TP*CP*AP*CP*AP*CP*CP*T)-3'), DNA (5'-D(*AP*GP*GP*TP*GP*TP*GP*AP*GP*CP*CP*T)-3'), T-box transcription factor T Authors: Newman, J.A, Gavard, A.E, von Delft, F, Gileadi, O, Bountra, C. Deposit date: 2023-01-31 Release date: 2023-03-22 Last modified: 2025-02-26 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Structural insights into human brachyury DNA recognition and discovery of progressible binders for cancer therapy. Nat Commun, 16, 2025
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2023-01-31
