Cellular Turnover Protocol™ – A Unified Therapeutic Framework for Apoptosis Regulation, Cellular Renewal, and Regenerative Medicine

The Cellular Turnover Protocol™ (CTP), developed by Dr. med. Dimitrios Mavrogeorgis, introduces a novel therapeutic paradigm based on the regulation of cellular turnover as a central mechanism in neurodegeneration, chronic disease, and aging. The framework unifies apoptosis, autophagy, microglial clearance, and metabolic renewal into a coordinated therapeutic model, proposing that targeted modulation of the cellular life–death cycle can become a foundational strategy for regenerative medicine. This white paper presents the full theoretical foundations, mechanistic rationale, and proposed clinical framework of the CTP, positioning it as the first structured attempt to address cellular turnover as a modifiable therapeutic axis. It further explores potential translational pathways and future directions for research and clinical application. Certain applied methodologies and proprietary implementation details remain confidential and are available only within the context of formal scientific collaboration or licensing. Citation of this document and its DOI is required in any derivative work, adaptation, or research building upon this framework.