Cryo-EM Structure of FGF23-FGFR1c-aKlotho-HS Quaternary Complex

Cryo-EM Structure of FGF23-FGFR1c-aKlotho-HS Quaternary Complex Descriptor: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, COPPER (II) ION, Fibroblast growth factor 23, ... Authors: Mohammadi, M, Chen, L. Deposit date: 2022-08-12 Release date: 2023-04-19 Last modified: 2025-06-18 Method: ELECTRON MICROSCOPY (2.74 Å) Cite: Structural basis for FGF hormone signalling. Nature, 618, 2023