Analysis of BRAF variant gene expression activity after constitutive variant expression in immortalized lung ephithelial cells. The hypothesis tested in the present study was that the level of BRAF ac
Philadelphia-chromosome negative myeloproliferative neoplasms (MPNs) including polycythemia vera, essential thrombocythemia and primary myelofibrosis show an inherent tendency for transformation into
The remarkable evolutionary capacity of cancer poses major challenges to current therapeutic efforts, and results from the vast clonal heterogeneity and ability of individual cancer cells to adapt to
