Gene expression profile at single cell level of terminal ileum tissues from healthy humans and atopic dermatitis

Atopic dermatitis is one of the most common inflammatory disorders characterized by intense itch and widespread inflammatory eczematous lesion, while the exact mechanism underlying the pathogenesis of AD, remains not completely clear. Moreover, whether there is a certain degree of intestinal changes in patients with AD also remains to be further studied. scRNA-seq enables specific profiling of cell populations at single-cell resolution. Here, we analyzed cells from AD and matched healthy adult terminal ileums at single-cell resolution Single-cell mRNA profiles of p terminal ileum tissues from healthy humans and atopic dermatitis were generated by Single-cell RNA sequencing, using BD Rhapsody system.