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CRISPR-Cas9 combinatorial KO of epigenetic regulators in human ovarian cancer cells

ChEBI2015-12-17 更新2026-07-12 收录

癌症基因筛查

表观遗传调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-71074 数据链接链接失效反馈

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资源简介：

CRISPR-Cas9 combinatorial KO of epigenetic regulators in human ovarian cancer cells

应用场景：

创建时间：

2015-12-17

变异功能预测

表观遗传调控

ncVarPred-1D3D: pretrained models of Sei (PMID: 35817977) + our 3D structure embedding models are shared. The models are trained and validated using DeepSEA (PMID: 26301843) selected 200 bp regions (w

Zenodo2023-08-08 更新00

Automethylated PRC2 dimer bound to nucleosome

表观遗传调控

PRC2-核小体复合物结构

Automethylated PRC2 dimer bound to nucleosome

NIAID Data Ecosystem00

ARID1B regulates BCL11B-mediated non-canonical Activin signaling to maintain mesenchymal stem cell homeostasis in the mouse incisor [scRNA-seq]

干细胞稳态

表观遗传调控

ARID1B is a epigenetic regulator. We used the scRNA sequencing to analysis the role of ARID1B in regulating mouse incisor tissue homeostasis. Single-cell transcriptomes were obtained from the digested

NIAID Data Ecosystem00

ChIP Seq of influenza specific primary, memory and secondary CD4+ T cells [InVitro]

表观遗传调控

CD4+T细胞记忆

Immune responses to infection involve a careful balance: too weak a response allows pathogen replication; too strong risks immunopathology. The immunoregulatory cytokine IL-10 is a key factor in this

NIAID Data Ecosystem00

DNMT3A Reads and Connects Histone H3K36me2 to DNA methylation [RNA-seq]

表观遗传调控

甲基化反应机制

DNA methylation at the 5-position of cytosine (5mC) is a crucial epigenetic mark in regulating biological processes including gene silencing, gene imprinting, and X chromosome inactivation. It has lon

NIAID Data Ecosystem00

CRISPR-Cas9 combinatorial KO of epigenetic regulators in human ovarian cancer cells

资源简介：

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