Lines of Plasmodium falciparum malaria parasites were selected for resistance to candidate antimalarial compounds in vitro and sequenced to determine mutational changes associated with resistance.
We herein report unsymmetrical coupling of 2-methylquinolines under the blue LED light conditions using iridium-based photocatalyst. This methodology represents the direct synthetic method for the β-n
Twenty-three aminooxy compounds have been examined for their ability to inhibit the growth of the malaria parasite Plasmodium falciparum in vitro. Eight of these compounds were found to have 50% inhib
