Genome-wide DNA methylation profiling in Atherosclerotic plaques. Genome-wide DNA methylation profiling in Atherosclerotic plaques

Genome wide Methylation profiling of DNA extracted from plaques of atherosclerotic plaque samples (n=14) and of controls (n=4). The Illumina Infinium HumanMethylation450 or HumanMethylation850 BeadChip was used representing potentially methylated CpG sites throughout the genome. Overall design: Bisulphite converted DNA from the 18 samples(n=4 controls, n=8 stable plaques and n=6 unstable plaques) were hybridized to the Illumina Infinium Human Methylation450 or Methylation850 Beadchip