Epigenetic profiling of Fetal Alcohol Spectrum Disorder (FASD) Discovery. Epigenetic profiling of Fetal Alcohol Spectrum Disorder (FASD) Discovery

Genome wide DNA methylation profiling of FASD patients versus healthy unexposed controls. The Illumina Infinium 450k Human DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 485,000 CpGs in peripheral blood samples. Samples included 64 healthy controls and 39 FASD patients. Overall design: Bisulfite converted DNA from the 103 samples were hybridized to the Illumina Infinium 450k Human Methylation Beadchip