Comprehensive transcriptome profile of AGS gastric cancer cells treated with flavonoid prunetin

Gastric cancer is the common type of malignancy positioned at second in mortality rate causing burden worldwide with increasing treatment options. The application of transcriptomics technologies possesses the high efficiency of identifying key metabolic pathways and functional genes in cancer research.Prunetin (PRU) is an O-methylated flavonoid that belongs to the group of isoflavone executing beneficial activities. In the current study, a transcriptome profile on treated and untreated conditions of flavonoid prunetin was performed in order identify the differential expression of genes which eventually aids in preditcing candidate biomarkers. Overall design: Identification of differentially expressed genes on treatment with prunetin in gastric cancer