Stem cell gene expression profiling of primary mammary tumors derived from orthotopic xenograft tumors treated with Sulforaphane (SFN) or control II. Homo sapiens

In this study, we explored stem cell markers profile of mammary tumor initiation and growth derived from a human breast cancer cell line (MDA-MB-231 D3H1 Luci). In this dataset, we include expression data from primary mammary tumors pre-treated with Sulforaphane for 2 weeks (daily i.p. injection of 50mg SFN/kg) and kept treatment after cell injection for more 3 weeks and Saline 0.9% as a Control. Overall design: In total, 36 samples were analyzed. We used a commercially available NanoString nCounter Human Stem Cell. We generated the following pairwise comparison using nSolver version 2.070: SFN vs. Saline. Genes with a p-value < 0.05 and an absolute fold-change of 1.5 were selected.