Crystal structure of the p53 cancer mutant Y220C in complex with a trifluorinated derivative of the small molecule stabilizer Phikan083
收藏Protein Data Bank Japan2024-01-10 更新2026-03-21 收录
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Crystal structure of the p53 cancer mutant Y220C in complex with a trifluorinated derivative of the small molecule stabilizer Phikan083 Descriptor: CELLULAR TUMOR ANTIGEN P53, N,N-dimethyl-1-[9-(2,2,2-trifluoroethyl)-9H-carbazol-3-yl]methanamine, ZINC ION Authors: Joerger, A.C, Bauer, M, Baud, M.G.J, Spencer, J. Deposit date: 2016-05-13 Release date: 2016-06-22 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.48 Å) Cite: Harnessing Fluorine-Sulfur Contacts and Multipolar Interactions for the Design of P53 Mutant Y220C Rescue Drugs. Acs Chem.Biol., 11, 2016
创建时间：
2016-05-13
