Crystal structure of human transthyretin in complex with 3-O-methyltolcapone analogue 1

Crystal structure of human transthyretin in complex with 3-O-methyltolcapone analogue 1 Descriptor: (3,5-dimethylphenyl)(4-hydroxy-3-methoxy-5-nitrophenyl)methanone, Transthyretin Authors: Poonsiri, T, Benini, S, Loconte, V, Cianci, M. Deposit date: 2023-01-18 Release date: 2024-01-17 Last modified: 2026-04-15 Method: X-RAY DIFFRACTION (1.19 Å) Cite: 3-O-Methyltolcapone and Its Lipophilic Analogues Are Potent Inhibitors of Transthyretin Amyloidogenesis with High Permeability and Low Toxicity. Int J Mol Sci, 25, 2023