Crystal structure of human TRF1 TRFH domain in complex with compound 48
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Crystal structure of human TRF1 TRFH domain in complex with compound 48 Descriptor: 1,2-ETHANEDIOL, 5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, CALCIUM ION, ... Authors: Casale, G, Le Bihan, Y.-V, van Montfort, R.L.M, Guettler, S. Deposit date: 2024-11-11 Release date: 2025-11-19 Last modified: 2025-12-03 Method: X-RAY DIFFRACTION (1.931 Å) Cite: Discovery of first-in-class inhibitors of the TRF1:TIN2 protein:protein interaction by fragment screening. Sci Rep, 15, 2025
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2024-11-11
