Blockage of retinoic acid signaling via RARγ suppressed the proliferation of pancreatic cancer cells by arresting the cell cycle progression of the G1-S phase. Blockage of retinoic acid signaling via RARγ suppressed the proliferation of pancreatic cancer cells by arresting the cell cycle progression of the G1-S phase

Blockage of RARγ signaling broadly downregulated the gene expression associated with the cell cycle progression of the G1-S phase and DNA synthesis in PDAC cells Overall design: Comparison of the gene expression profiles between control and RARγi-treated cells using PDAC cell lines (PK-1 and Panc-1)