Incremental cost-effectiveness of influenza vaccination strategies targeting children and older adults implemented in the Canadian population: base case, with trivalent influenza vaccination in individuals aged 6–64.

Abbreviations: TIV, trivalent inactivated vaccine; ATIV, adjuvanted trivalent inactivated vaccine. a2009 Canadian dollars, discounted at 5% annually over a 10-year time horizon. bQuality-adjusted life years lost, discounted at 5% annual over a 10-year time horizon. cImmunization of older adults only with ATIV was economically attractive at $2111 per QALY, but the incremental cost-effectiveness ratio of immunizing both older adults and young children with ATIV was <$500 per QALY, indicating “extended dominance”.