IPA top functions and corresponding bio-functions up- or down-regulated by <i>Mmm</i> infection.

p-values were calculated with the Fisher exact test. Z-scores were calculated with the IPA z-score algorithm. The z-score predicts the direction of change of a function. An absolute z-score ≥ 2 was considered to be significant. A bias-corrected z-score* was calculated by IPA to correct dataset bias, i.e., when there are more up- than down-regulated genes or vice-versa. “genes” indicates the number of genes that are associated with each function. A function is predicted to be decreased (DOWN) if the z-score (or the bias corrected z-score) ≤ 2 and increased (UP) if the z-score≥2. IPA top functions and corresponding bio-functions up- or down-regulated by Mmm infection.