Clinical Characteristics of Subjects studied in Stage One and Two Screening.

*IOP; intra ocular pressure (under medication).**The Visual Field Score was evaluated by Humphrey MD value or Goldmann perimetry (Stage One) and Humphrey MD value (Stage Two).In Stage One, the severity of the visual field defects was scored from 1 to 5 according to previously reported criteria. The data obtained by two types of perimetry were combined using a five-point scale: 1, no alterations; 2, early defects; 3, moderate defects; 4, severe defects; and 5, light perception only or no light perception. The first four groups on this severity scale followed Kozaki's classification based on Goldmann perimetry or the classification was based on results of visual field perimetry (Humphrey Field Analyzer; Carl Zeiss Meditec, Dublin, CA). Kozaki's classification is widely used in Japan.