Crystal structure of GRL-8234 bound to BACE (Beta-secretase)
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Crystal structure of GRL-8234 bound to BACE (Beta-secretase) Descriptor: BETA-SECRETASE 1, N-{(1S,2R)-1-benzyl-2-hydroxy-3-[(3-methoxybenzyl)amino]propyl}-5-[methyl(methylsulfonyl)amino]-N'-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide Authors: Hong, L, Tang, J, Ghosh, A.K. Deposit date: 2007-12-04 Release date: 2008-12-16 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Potent Memapsin 2 (Beta-Secretase) Inhibitors: Design, Synthesis, Protein-Ligand X-Ray Structure, and in Vivo Evaluation. Bioorg.Med.Chem.Lett., 18, 2008
创建时间:
2007-12-04



