Additional file 1 of Dissection of multiple sclerosis genetics identifies B and CD4+ T cells as driver cell subsets

Additional file 1: Supplementary Tables. Table S1. MS GWAS enrichment in 16 hematopoietic cell types. Table S2. MS GWAS enrichment of hematopoietic cell types in joint model. Table S3. MS GWAS pairwise enrichment in 16 hematopoietic cell types. Table S4. MS GWAS cell-specific enrichment within terminal hematopoietic cell types. Table S5. Heritability enrichments (single model) for other disorders. Table S7. MS GWAS enrichment in CD4+ T cell subpopulations. Table S8. Stratified LDSC in CD4+ T cell subpopulations. Table S9. MS GWAS pairwise enrichment in CD4+ T subpopulations. Table S10. MS GWAS enrichment in B cell subpopulations. Table S11. Stratified LDSC in B cell subpopulations. Table S12. MS GWAS pairwise enrichment in B cell subpopulations. Table S13. Clinical characteristics of MS subjects. Table S14. MS GWAS enrichment across OCRs in 6 cell types isolated from untreated MS patients. Table S15. MS GWAS enrichment across OCRs in joint model in CD4 T cell types isolated from untreated MS patients. Table S16. MS GWAS enrichment across OCRs in joint model in B cell types isolated from untreated MS patients. Table S17. MS GWAS enrichment across OCRs in 6 cell types isolated from treated MS patients. Table S18. MS GWAS enrichment across OCRs in joint model in T4em isolated from untreated and treated MS patients. Table S19. MS GWAS enrichment across OCRs in joint model in cMBc isolated from untreated and treated MS patients. Table S20. MS GWAS enrichments in histone ChIP-seq from Th17 cells. Table S21. MS GWAS enrichments in histone ChIP-seq from B cells. Table S20. MS GWAS enrichments in chromatin states from Th17 cells. Table S21. MS GWAS enrichments in chromatin states from B cells. Table S24. MS fine-mapping enrichments in ATAC-seq OCRs. Table S25. Pairwise enrichments of MS fine-mapped SNPs in OCRs Index cell types are shown on the left. Table S26. MS fine-mapping enrichments in PCHiC + ATAC-seq OCRs. Table S27. Summary of gene prioritizations. Table S28. Canonical pathway enrichment for prioritized MS genes. Table S29. Protein-protein interaction connectivity summaries for prioritized gene lists. Table S30. CD4 T prioritized genes ranked in the opposite extreme 10% of gene expression changes in KD and OE cell lines. Table S31. B prioritized genes ranked in the opposite extreme 10% of gene expression changes in KD and OE cell lines. Table S32. Markers for FACS sorting strategy of Verily ATAC-seq data.