Crystal structure of FGFR3 in complex with pyrimidine derivative
收藏Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/7dhl
下载链接
链接失效反馈官方服务：
资源简介：
Crystal structure of FGFR3 in complex with pyrimidine derivative Descriptor: 5-[2-(3,5-dimethoxyphenyl)ethyl]-N-[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]pyrimidin-2-amine, Fibroblast growth factor receptor 3 Authors: Echizen, Y, Tateishi, Y, Amano, Y. Deposit date: 2020-11-16 Release date: 2021-02-03 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.57 Å) Cite: Synthesis and structure-activity relationships of pyrimidine derivatives as potent and orally active FGFR3 inhibitors with both increased systemic exposure and enhanced in vitro potency. Bioorg.Med.Chem., 33, 2021
创建时间：
2020-11-16
