Two new prenylated indole diketopiperazine alkaloids (PIDAs) penicamides A and B (1 and 2) and three new polyketides penicinones A−C (6−8), along with four known compounds deoxybrevianamide E (3), bre
Poly (ADP-ribose) polymerase 1 (PARP-1) is a critical enzyme involved in DNA damage repair and recombination, and shows great potential for drug development in the treatment of cancers with defective
Selenocyano fragments with distinct structural characteristics were successfully incorporated into the 5- and 7-positions of chrysin via etherification and esterification of its hydroxyl groups. Eleve
Compounds 13 and 14 were evaluated against 11 PARP isoforms to reveal that both 13 and 14 were more potent and isoform selective toward inhibiting tankyrases (TNKSs) than the “standard” inhibitor 1 (X
This dataset is the research data of the article titled "Terpenoids from Daphne pedunculata and Their Cytotoxic Activities In Vitro". The highlights of the research are: 1. Three new terpenoids, inclu
