Poly (ADP-ribose) polymerase 1 (PARP-1) is a critical enzyme involved in DNA damage repair and recombination, and shows great potential for drug development in the treatment of cancers with defective
Glioblastoma therapy relies on the alkylating drug temozolomide (TMZ) administered to irradiated patients post-neurosurgery, which increases overall survival but cannot prevent fatal disease relapse.
This dataset contains RNA sequencing data of cancerous HCT-116 and non-cancerous intestinal IPEC-J2 cells treated with curcumin, three curcumin-based benzothiazepane analogues, and untreated controls.
