Adjusted odds ratios for developing airway obstruction (FEV1/FVC<0.7) and respiratory symptoms over 11 years of follow-up comparing different <i>SERPINA1</i> genotypes.

CI: confidence interval. hs-CRP: high-sensitivity C-reactive protein. OR: odds ratio. Covariates included sex, linear and squared age, recruiting area, smoking history (packyears at baseline, as well as linear and squared packyears between baseline and follow-up), height, baseline BMI and BMI change between baseline and follow-up. aPersistent smokers were classified as subjects who declared current smoking at both examinations. bObese subjects were defined as BMI≥30kg/m2 at the baseline or follow-up examination. cCorresponded to a level of ≥ 1.8 mg/l.