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X-ray crystal structure of ITK complexed with inhibitor BMS-509744

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Protein Data Bank Japan2023-09-06 更新2026-03-21 收录
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X-ray crystal structure of ITK complexed with inhibitor BMS-509744 Descriptor: N-[5-({5-[(4-acetylpiperazin-1-yl)carbonyl]-4-methoxy-2-methylphenyl}sulfanyl)-1,3-thiazol-2-yl]-4-({[(1S)-1,2,2-trimethylpropyl]amino}methyl)benzamide, Tyrosine-protein kinase ITK/TSK Authors: Kuglstatter, A, Villasenor, A.G. Deposit date: 2010-04-12 Release date: 2010-06-30 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structures of IL-2-inducible T cell kinase complexed with inhibitors: insights into rational drug design and activity regulation. Chem.Biol.Drug Des., 76, 2010

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2010-04-12
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