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Trancriptomic profiling of HCT116 colon cancer cells with or without PBRM1 knock-down by RNAi

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NIAID Data Ecosystem2026-05-01 收录
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To investigate the influence of PBRM1 on gene expression, we performed RNA-seq in HCT116 colon cancer cells with or without PBRM1 knock-down by RNAi (both shRNA and siRNA approaches were used), and identified differentially expressed genes in PBRM1 knock-down cells compared to control cells, which shows implications for PBRM1's biological function in colon cancer.

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2023-10-13
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