ARID3a expression in human hematopoietic stem cells is associated with distinct gene patterns in aged individuals. ARID3a expression in human hematopoietic stem cells is associated with distinct gene patterns in aged individuals

Aging results in altered gene expression patters in HSCs expressing ARID3A transcirpts, with a number of genes downregulated in aged donor ARID3a+ HSCs compared to young donor ARID3a+ HSCs Overall design: scRNA-seq of isolated peripheral blood HSCs from young and aged donors.