H3K4 demethylation by Jarid1a and Jarid1b contributes to retinoblastoma-mediated gene silencing during cellular senescence (ChIP-seq)
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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Cellular senescence is a tumor-suppressive program that involves chromatin reorganization and specific changes in gene expression that trigger an irreversible cell-cycle arrest. We combined quantitative mass spectrometry and ChIP deep-sequencing to identify changes in histone modification occurring during cellular senescence.
提供机构:
Memorial Sloan Kettering
创建时间:
2022-02-20



