PCSK9 in complex with a Fab and compound 8
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PCSK9 in complex with a Fab and compound 8 Descriptor: 2-fluoro-4-{[(1R)-1-methyl-6-{[(2S)-oxan-2-yl]methoxy}-1-{2-oxo-2-[(1,3-thiazol-2-yl)amino]ethyl}-1,2,3,4-tetrahydroisoquinolin-7-yl]oxy}benzoic acid, Fab Heavy Chain, Fab Light Chain, ... Authors: Lu, J, Soisson, S. Deposit date: 2019-08-21 Release date: 2019-11-06 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.73 Å) Cite: From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9. Cell Chem Biol, 27, 2020
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2019-08-21
