The purpose of the study is to investigate the safety, tolerability, and preliminary anti-neoplastic activity of S095029 alone and in combination with Sym021 in patients with advanced solid tumor mali
Chimeric antigen receptor (CAR) T cell therapy has shown remarkable clinical success in the treatment of B-cell acute lymphoblastic leukemia (B-ALL), non-Hodgkin lymphoma (NHL), and multiple myeloma (
*Adverse events leading to study drug discontinuation: Immediate Switch: emergent to EFV/FTC/TDF—anxiety; insomnia; night sweatsDelayed Switch: emergent to ABC/3TC + EFV (baseline to Wk12)—depressionD