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CASZ1 is essential for activation of epidermal terminal differentiation

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NIAID Data Ecosystem2026-05-10 收录
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CASZ1 is a novel and potent activator of terminal epidermal differentiation. CASZ1 knockdown inhibits transcription of the epidermal differentiation program. p63 and p300 are required to activate CASZ1 expression. RNA-sequencing of control and CASZ1 siRNA-treated keratinocytes in the differentiated condition. 2 replicates per condition. ChIP-sequencing of p63 and H3K27ac in progenitor and differentiated keratinocytes. 2 replicates per condition.

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2025-09-23
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