Keap1 deletion-based Nrf2 activation accelerates mutant K-ras/p53-driven cholangiocarcinoma
收藏NIAID Data Ecosystem2026-03-12 收录
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资源简介：
Addition of liver-specific Keap1 deletion to mice harboring mutant K-ras and p53 accelerated cholangiocarcinoma formation, with hallmarks of Nrf2 activation. We introduced liver-specific mutant K-rasG12D and p53R172H expressions with (AKP::Keap1 mouse) or without (AKP mouse) Keap1 deletion.
创建时间：
2021-09-28
