General overview of human-worm complex I subunit and subcomplex homology.

Notes:Two strains were studied for homologues of two I�� subunits, NDUFS2 and NDUFA2 - see Table 1 notes for details.**I�� consists of ��breakthrough fractions�� in the purification of subcomplexes I�� and I�� from bovine heart mitochondria, but only KFY1.Extensive conservation is apparent between human and C. elegans complex I composition, as broken down by either genome of origin or subcomplex. ��Percent conserved�� indicates the number of human complex I subunits in each group for which a C. elegans homologue can be identified, rather than the extent of similarity between specific subunits. *, two strains each were studied for homologues of two 1�� subunits, NDUFS2 and NDUFA2, per details in Table 1 legend. **, only KFY1 is found in no other fraction except 1��. *** MLRQ is not localized to any subcomplex (4).