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The evolutionary history of effectors downstream of Cdc42 and Rac

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PubMed Central2002-01-14 更新2026-05-25 收录
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Cdc42 and Rac - ancient, highly conserved, small GTPases - mediate extracellular signals, triggering changes in transcription and in the actin cytoskeleton. Although dozens of proteins act downstream of these GTPases, a comparison of effector proteins from evolutionarily diverse organisms suggests that six groups of proteins serve as the core machinery for signaling from Cdc42 and Rac.

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BMC
创建时间:
2002-01-14
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