Controlling fibrosis using compound with novel binding mode to prolyl-tRNA synthetase 1

Controlling fibrosis using compound with novel binding mode to prolyl-tRNA synthetase 1 Descriptor: 1-(5-chloranyl-4-methyl-benzimidazol-1-yl)-3-[(2R,3S)-3-oxidanylpiperidin-2-yl]propan-2-one, ADENOSINE-5'-TRIPHOSPHATE, Bifunctional glutamate/proline--tRNA ligase, ... Authors: Kim, S, Yoon, I, Son, J, Park, S, Hwang, K.Y. Deposit date: 2022-06-08 Release date: 2023-07-05 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Control of fibrosis with enhanced safety via asymmetric inhibition of prolyl-tRNA synthetase 1. Embo Mol Med, 15, 2023