Genome-wide analysis of ferroptosis related genes in liver cancer cells.

To seek ferroptosis related genes in liver cancer cells, we treated HepG2 cells using ferroptosis inducer Erastin and inhibitor Ferrostatin, respectively. We found that a subset of genes were up-regulated in Erastin treatment groups and down-regulated in Ferrostatin treatment groups, suggesting that these genes might be correlated with ferroptosis. Overall design: Examination of ferroptosis related genes in HepG2 cells.