Inhibitor Bound to A DFG-Out structure of the Kinase Domain of CSF-1R
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Inhibitor Bound to A DFG-Out structure of the Kinase Domain of CSF-1R Descriptor: 3-({4-methoxy-5-[(4-methoxybenzyl)oxy]pyridin-2-yl}methoxy)-5-(1-methyl-1H-pyrazol-4-yl)pyrazin-2-amine, Macrophage colony-stimulating factor 1 receptor Authors: Kamtekar, S, Day, J.E, Reitz, B.A, Mathis, K.J, Meyers, M.J. Deposit date: 2010-01-11 Release date: 2010-09-15 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Structure-based drug design enables conversion of a DFG-in binding CSF-1R kinase inhibitor to a DFG-out binding mode. Bioorg.Med.Chem.Lett., 20, 2010
创建时间：
2010-01-11
