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Crystal Structure of MMP-13 Complexed with Inhibitor 24f

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Protein Data Bank Japan2024-02-21 更新2026-03-21 收录
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Crystal Structure of MMP-13 Complexed with Inhibitor 24f Descriptor: (2R)-({[5-(4-ethoxyphenyl)thiophen-2-yl]sulfonyl}amino){1-[(1-methylethoxy)carbonyl]piperidin-4-yl}ethanoic acid, CALCIUM ION, Collagenase 3, ... Authors: Kulathila, R, Monovich, L, Koehn, J. Deposit date: 2008-09-22 Release date: 2009-07-21 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Discovery of potent, selective, and orally active carboxylic acid based inhibitors of matrix metalloproteinase-13 J.Med.Chem., 52, 2009
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2008-09-22
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