Adverse events: graft failure, GVHD, no response, overall mortality.

–: information extractable from publication.*Bayever 1984: acute GVHD including interstitial pneumonia; chronic GVHD including moderate or severe types. Abbreviations: GVHD: graft-versus-host disease; HSCT: hematopoietic stem cell transplantation; IST: immunosuppressive therapy.†Bacigalupo 2000: less acute GVHD with methotrexate plus cyclosporine A vs. methotrexate or cyclosporine A alone; incidence of acute GVHD III to IV has been reduced from 20% to 6% with time (pI has not improved with time; incidence of extensive chronic GVHD has been reduced from 15% to 5% with time (pAbbreviations: GVHD: graft-versus-host disease; HSCT: hematopoietic stem cell transplantation; IST: immunosuppressive therapy.